Biology 0610/32 February/March 2025: question paper and mark scheme
Cambridge IGCSE Biology (0610), Paper 3 Theory (Core), February/March 2025. Read both free below, or download them. Done the paper? Get it marked by AI against this mark scheme.
(a) Complete the sentences to describe enzymes.
Use words or phrases from the list.
Each word or phrase may be used once, more than once or not at all.
amino acids calcium carbon fatty acids hydrogen
iron magnesium molecules nitrogen oxygen water
Enzymes are proteins. All proteins are made up from a chain of smaller
…… called …… .
All proteins contain the chemical elements …… ,
…… , …… and …… .
[4]
(b) Enzymes function as biological catalysts.
Describe what is meant by the term catalyst.
…… [2]
(c) Fig. 1.1 shows a reaction catalysed by an enzyme.
substrate
enzyme
Fig. 1.1
Use Fig. 1.1 to describe enzyme action.
…… [3]
(d) Some bacteria are found living in very high temperatures.
Fig. 1.2 shows the effect of temperature on the activity of an enzyme in these bacteria.
12
10
8 enzyme activity
/ arbitrary units
6
4
2
0
0 10 20 30 40 50 60 70
temperature / °C
Fig. 1.2
Using the information in Fig.1.2:
(i) Identify the optimum temperature for this enzyme.
…… °C [1]
(ii) Identify the temperature when the enzyme is completely denatured.
Explain how you identified your choice.
temperature …… °C
explanation ……
[2]
(iii) Calculate the difference in enzyme activity between 20 °C and 40 °C.
Space for working.
…… arbitrary units [2]
(iv) The mean body temperature for humans is 37 °C.
On Fig. 1.2, sketch the curve for the activity of an enzyme found in humans. [2]
[Total: 16]
Mark scheme
1(a) molecules ; 4
amino acids ;
carbon and hydrogen and oxygen ; A elements in any order for MP3 and 4
nitrogen ;
1(b) (substance that) increase the rate of a (chemical) reaction ; 2
not changed by the reaction / not (permanently) used up ;
1(c) any three from: 3
1 substrate and enzyme combine / join together / AW ;
2 (at the) active site / where shapes fit together / where shapes are
complementary / where shape of the sites mirror each other / AW ;
3 bond/s in substrate broken / AW ;
4 products, released / leave enzyme ;
5 enzyme free to act on more substrate / AW ;
1(d)(i) 50 ± 1 ; 1
1(d)(ii) 66 (°C) ; 2
zero activity / no enzyme activity ;
1(d)(iii) 7.2 ;; 2 MP1: 2.8 and 10 seen
MP2: difference calculated between values
in MP1 (ecf)
1(d)(iv) same shaped curve (gradual rising to a peak with sharp decline) ; 2
optimum around 37 °C ±2 ;
(a) Fig. 2.1 shows the human digestive system.
A
B
C
D
E
F
G
H
J
K
Fig. 2.1
(i) The human digestive system is made up of the alimentary canal and the associated organs.
Food moves through the alimentary canal, but does not move through the associated organs.
The pancreas is one of the associated organs.
State the letter in Fig. 2.1 that identifies the pancreas and state the name of two enzymes secreted by the pancreas.
letter ……
enzyme 1 ……
enzyme 2 ……
[3]
(ii) State one letter in Fig. 2.1 that identifies one other associated organ of the digestive system.
Name this organ.
letter …… name ……
[1]
(iii) In Fig. 2.1, structure J is the small intestine.
State two functions of the small intestine.
1 ……
2 ……
[2]
(b) Some antibiotics are taken into the body as tablets.
Fig. 2.2 shows the concentration of antibiotic in the blood after a tablet is taken.
2.0
1.5
concentration of antibiotic in blood 1.0
/ arbitrary units
0.5
0
0 2 4 6 8 10 time after antibiotic is taken / hours
Fig. 2.2
(i) Using Fig. 2.2, describe how the concentration of antibiotic in the blood changes.
…… [3]
(ii) Circle the name of the process of taking substances into the body.
assimilation digestion egestion excretion ingestion [1]
(iii) Antibiotics are transported around the body by the blood.
State the name of the component of blood that transports substances such as nutrients, hormones and antibiotics.
…… [1]
(iv) State the type of organism killed by antibiotics.
…… [1]
[Total: 12]
Mark scheme
2(a)(i) G; 3
any two from:
(named) amylase ;
(named) protease ;
(named) lipase ;
2(a)(ii) any one from: 1
B and salivary glands ;
D and liver ;
E and gall bladder ;
2(a)(iii) any two from: 2
(chemical) digestion / description of ;
absorption of, nutrients / digested substances / named nutrient ;
2(b)(i) any three from: 3
1 state (concentration) increases then decreases ;
2 (concentration), increases rapidly / decreases gradually / AW ;
3 reaches a peak / greatest concentration at, 2 hours / 1.8 au ;
4 antibiotic remains in the blood after 10 hours ;
5 additional data quote(not given in MP3 or MP4) using information / units
from both axes ;
2(b)(ii) ingestion circled ; 1
2(b)(iii) plasma ; 1
2(b)(iv) bacteria ; 1
(a) Fig. 3.1 shows blood flow through a human heart.
The arrows show the direction of blood flow.
A
B
C
septum
Fig. 3.1
(i) On Fig. 3.1, draw a label line and the letter X to identify the muscular wall of the left ventricle. [1]
(ii) Describe the path taken by blood as it moves from A to B in Fig. 3.1.
…… [3]
(iii) State the name of blood vessel C shown in Fig. 3.1.
…… [1]
(b) The activity of the heart can be monitored using an ECG.
Fig. 3.2 shows the results of an ECG for a person who has been resting for 15 minutes.
one heart beat
Fig. 3.2
Fig. 3.3 shows the results of ECGs for the same person:
• resting
• during vigorous physical activity
• one minute after physical activity
• one hour after physical activity.
(i) Draw lines to link each activity with its ECG. Draw three lines.
One has been done for you.
activity ECG
resting
during vigorous physical activity
one minute after physical activity
one hour after physical activity
Fig. 3.3
[2]
(ii) State two other ways that the activity of the heart can be monitored.
1 ……
2 ……
[2]
(c) During vigorous physical activity humans respire anaerobically.
(i) Tick (✓) three statements that describe anaerobic respiration in humans.
alcohol is produced
carbon dioxide is produced
glucose is required
lactic acid is produced
oxygen is required
releases less energy per substrate molecule than aerobic respiration
[3]
(ii) State how vigorous exercise affects the rate and depth of breathing.
rate ……
depth ……
[1]
[Total: 13]
Mark scheme
3(a)(i) labelled line with X to wall of the left ventricle ; 1
3(a)(ii) (from A) into (right) atrium ; 3
into (right) ventricle ;
ref to movement through, valve / named valve ;
3(a)(iii) pulmonary vein ; 1
3(b)(i) 2 3 correct = 2 marks
1–2 correct = 1 mark
;;
3(b)(ii) any two from: 2
(counting the) pulse rate ;
listening to the sound (of the valves) ;
AVP ; e.g. blood pressure monitor
3(c)(i) 3 1 mark for each correct tick
alcohol is produced
R each additional tick
carbon dioxide is produced
glucose is required ✓;
lactic acid is produced ✓;
oxygen is required
releases less energy per ✓;
substrate molecule than aerobic
respiration
3(c)(ii) rate: increases and 1
depth: increases ;
Fig. 4.1 shows part of a leaf from a Mexican hat plant.
offspring
Fig. 4.1
(a) The Mexican hat plant shown in Fig. 4.1 is reproducing.
Tick (✓) three statements that describe the reproduction shown in Fig. 4.1.
Gametes are produced.
Involves implantation.
Only one parent is involved.
Pollination occurs before the stage shown in Fig. 4.1.
The offspring are genetically identical to each other.
The reproduction is asexual.
[3]
(b) Fig. 4.2 shows a section of a flower.
L
M
N
Fig. 4.2
Identify structures L, M and N shown in Fig. 4.2.
L ……
M ……
N ……
[3]
(c) Fig. 4.3 shows a flower from a Crocus plant.
petals
Fig. 4.3
(i) Using the information in Fig. 4.3, predict the type of pollination used by the Crocus plant.
Explain your prediction.
prediction ……
explanation ……
[3]
(ii) Describe the process of pollination.
…… [2]
(d) Fig. 4.4 is a photomicrograph of pollen grains.
P
Q
W
R
V
S
0.03 mm T
Fig. 4.4
(i) State one letter in Fig. 4.4 that identifies a pollen grain from a wind-pollinated flower.
…… [1]
(ii) Using the information in Fig. 4.4, estimate the maximum length of pollen grain V.
Include the unit.
…… unit …… [2]
(iii) State two characteristics of pollen grains from insect-pollinated flowers.
1 ……
2 ……
[2]
[Total: 16]
Mark scheme
4(a) 3 1 mark for each correct tick
Gametes are produced.
R each additional tick
Involves implantation.
Only one parent is involved. ✓;
Pollination occurs before the stage shown in Fig. 4.1.
The offspring are genetically identical to each other. ✓;
The reproduction is asexual. ✓;
4(b) L filament ; 3
M ovule ;
N sepal ;
4(c)(i) prediction: 1+2 mark prediction and explanation
insect pollination ; independently
explanation:
any two from:
1 large petals ;
2 anthers / stamens, are not visible ;
3 stigma is not visible / stigma enclosed by petals ;
4(c)(ii) transfer of pollen ; 2
from an anther to a stigma ;
4(d)(i) Q/R; 1
4(d)(ii) 0.08–0.10 ; 2
mm ;
4(d)(iii) any two from: 2
spikes / hooks / rough ;
sticky ;
heavy ;
large (diameter) ;
(a) Fig. 5.1 shows a leaf insect on a leaf.
Fig. 5.1
(i) State one feature visible in Fig. 5.1 that identifies this leaf insect as an insect.
…… [1]
(ii) State one feature visible in Fig. 5.1 that identifies this leaf insect as an arthropod.
…… [1]
(b) The leaf insect in Fig. 5.1 has adaptive features.
(i) Describe the adaptive features visible in the insect shown in Fig. 5.1, and explain the importance of these features.
…… [3]
(ii) Complete the sentences by writing a suitable word in each space.
In a population of leaf insects there are differences between the individuals. The term for
the difference between individuals of the same species is …… .
Individuals that reproduce are able to pass on their …… to the
next generation. Over many generations the features of individuals that reproduce will
be more common in the population. This process is called ……
selection.
[3]
(c) Some species of leaf insect are endangered.
State three ways that endangered species can be conserved.
1 ……
2 ……
3 ……
[3]
[Total: 11]
Mark scheme
5(a)(i) any one from: 1
3 pairs of legs ;
body divided into, three parts / head, thorax and abdomen ;
one pair of antennae ;
5(a)(ii) jointed legs / jointed appendages / segmented body ; 1
5(b)(i) any three from: 3
features
body is wide and flat / (some) leg joints are wide and flat ;
looks like a leaf ;
importance
difficult for predators to see it ;
less likely to be eaten by a predator / more likely to, survive / reproduce ;
5(b)(ii) variation ; 3
alleles / genes ;
natural ;
5(c) any three from: 3
monitoring / counting species ;
idea of protecting habitats ; e.g. nature reserves, wildlife parks
education ;
captive breeding ; A zoo, sanctuary
seed banks ;
reduce hunting / predation / poaching ; A legislation
AVP ; e.g. remove invasive species
(a) Barley is a crop plant.
Fig. 6.1 shows the yield of barley per unit area of crops grown between 1945 and 2020.
8
C
6
yield of barley
/ tonnes per 4
B unit area
2
A
0
1940 1960 1980 2000 2020 year
Fig. 6.1
(i) Selective breeding of barley plants has increased the yield of barley.
Identify the period, A, B or C, when the largest increase in yield occurred.
Explain how you made your choice.
period ……
explanation ……
[2]
(ii) Using the information in Fig. 6.1, calculate the yield of barley in the year 2000 in kilograms per unit area.
One tonne = 1000 kg.
Space for working.
…… kg [2]
(iii) The list contains statements that describe selective breeding of barley plants to increase yield.
A Humans select barley plants with a high yield.
B New barley plants are grown.
C Offspring with a high yield are selected and bred together.
D Pollination and fertilisation occurs.
E Seeds form.
F The process is repeated over many generations.
Arrange the statements in the correct order to describe the process of selective breeding in barley plants.
Two have been done for you.
A B
[2]
(iv) State three other ways that humans can increase the yield of barley.
1 ……
2 ……
3 ……
[3]
(b) Barley can be grown as a monoculture.
(i) Describe what is meant by the term monoculture.
…… [1]
(ii) State one advantage and one disadvantage of growing crops as monocultures.
advantage ……
disadvantage ……
[2]
[Total: 12]
Mark scheme
6(a)(i) B; 2 marks are independent
steepest (part of) curve ;
6(a)(ii) 6400 (kg) ;; 2 MP1: 6.4 (tonnes per unit area) (seen)
MP2: value from graph × 1000
ecf from previous step
6(a)(iii) D in first gap and F at the end ; 2
E in second gap and C after B ;
6(a)(iv) any three from: 3
use (named) fertilisers ;
use (named), insecticides / pesticides ;
use (named) herbicides ;
use GM seeds ;
use, irrigation / drainage ;
deter animals that eat barley ;
AVP ;; e.g. crop rotation / plant seeds in
drills / cover seeds with soil / plant at
optimal spacing (for barley)/ plant as a
monoculture
6(b)(i) idea of only one type of plant grown / single crop grown / AW ; 1
6(b)(ii) max 1 from advantages: 2
1 allows large area of land to be used efficiently ;
2 increases (overall) yield ;
3 allows machinery to be used ;
4 allows farmers to specialise ;
5 AVP ; e.g. cheaper / costs less
max 1 from disadvantages:
1 increases insect pests ;
2 increases risk of disease ;
3 risks total crop failure ;
4 reduces biodiversity / AW ; e.g. extinction / loss of habitats / reduces
food for pollinators
5 depletes soil nutrients ;
6 AVP ; e.g. ref to pollution
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Biology 0610/32 for February/March 2025 is out of 80 marks, with 1 hour 15 minutes to answer it, across 6 questions.
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