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Biology 0610/42 February/March 2025: question paper and mark scheme

Cambridge IGCSE Biology (0610), Paper 4 Theory (Extended), February/March 2025. Read both free below, or download them. Done the paper? Get it marked by AI against this mark scheme.

0610_m25_qp_420610_m25_ms_420610/42/F/M/25

Paper
Paper 4 Theory (Extended)
Total marks
80
Time
1 hour 15 minutes
Questions
6
Code on the paper
0610/42/F/M/25
0610_m25_ms_42.pdf

0610/42 mark scheme, question by question

Each question as it's printed, and the mark scheme's points for it, as text. Diagrams, tables and graphs are in the PDFs above.

Question 116 marks

Question

Fig. 1.1 shows the movement of particles through an epithelial cell in the small intestine. P membrane of epithelial cell Q energy R Fig. 1.1 (a) In Fig. 1.1, arrow P represents the diffusion of oxygen molecules. (i) Describe what is meant by the term diffusion. …… [2] (ii) State the type of energy needed for diffusion. …… [1] (b) Carbon dioxide molecules also move by diffusion. (i) State the name of the process in human cells that produces carbon dioxide. …… [1] (ii) On Fig. 1.1, draw an arrow to show the direction of diffusion of carbon dioxide molecules. [1] (c) In Fig. 1.1, arrow Q represents another type of particle movement. Identify the type of particle movement represented by arrow Q. Explain your answer. type of movement …… explanation …… [3] (d) In Fig. 1.1, particle R moves from the lumen of the small intestine into the epithelial cell. Suggest why particle R cannot be starch. …… [2] (e) Fig. 1.2 is a photomicrograph of red onion cells. Fig. 1.2 Fig. 1.3 is a photomicrograph of the same red onion cells after being immersed in a salt solution. Fig. 1.3 Using Fig. 1.2 and Fig. 1.3, describe and explain the difference in appearance of the cells before and after immersion in salt solution. …… [6] [Total: 16]

Mark scheme

1(a)(i) net movement / AW, of particles ; 2 from a region of higher concentration to a region of their lower concentration (as a result of their random movement) ; 1(a)(ii) kinetic (energy) ; 1 1(b)(i) aerobic respiration ; 1 1(b)(ii) arrow drawn from inside to outside of epithelial cell ; 1 1(c) type: 3 active transport ; explanation: (particles move from) low(er) concentration to high(er) concentration ; uses energy ; 1(d) any two from: 2 starch is insoluble ; starch is (too) large ; starch has already been broken down / AW ; 1(e) any six from: 6 1 idea of before immersion cells are turgid / idea of after immersion cells are flaccid or plasmolysed ; 2 idea of before immersion cell membrane or cytoplasm pushes against cell wall / idea of after immersion cell membrane or cytoplasm pulls away from cell wall ; 3 idea of before immersion increased turgor pressure / idea of after immersion decreased turgor pressure ; 4 ref to osmosis ; 5 salt solution is concentrated or has a lower water potential / cytoplasm is dilute or has a higher water potential ; 6 water moves from high water potential to low water potential ; 7 through a partially permeable membrane ; 8 cytoplasm / vacuole / cell contents, is darker (after immersion) / ora ; 9 cytoplasm / vacuole / cell contents, are more concentrated (after immersion) / ora ;

Question 211 marks

Question

(a) The internal body temperature of a person was recorded. Fig. 2.1 shows the results. 39 38 internal body F 37 temperature / °C 36 35 time Fig. 2.1 (i) Using the information in Fig. 2.1, calculate the temperature range for the internal body temperature of the person. State the units. …… [1] (ii) On Fig. 2.1, draw a line to show the set point for the internal body temperature of the person. [1] (iii) The maintenance of internal body temperature is an example of homeostatic control. State the name of the mechanism for homeostatic control. …… [1] (iv) On Fig. 2.1, region F shows a change in body temperature. Explain how the body causes the change in body temperature shown. …… [5] (b) Fig. 2.2 shows a cross-section of human skin. E D capillaries arteriole C A B Fig. 2.2 (i) State the letter of the structure shown in Fig. 2.2 that produces sweat. …… [1] (ii) State the names of structures C and D shown in Fig. 2.2. C …… D …… [2] [Total: 11]

Mark scheme

2(a)(i) 2 and °C ; 1 2(a)(ii) horizontal line drawn at 37 °C ; 1 2(a)(iii) negative feedback ; 1 2(a)(iv) any five from: 5 1 brain / receptors, detect(s), low temperature / change in temperature ; 2 constriction of arterioles / vasoconstriction ; 3 less blood flow to, skin-surface / capillaries ; 4 ref to shivering / increased or rapid (skeletal) muscle contraction ; 5 increase in rate of respiration ; 6 hair erector muscles contract / hair stands on end ; 7 hair traps (insulating layer of) air ; 8 AVP ; 2(b)(i) A; 1 2(b)(ii) C – (hair) erector muscle ; 2 D – sensory neurone ;

Question 317 marks

Question

(a) Fig. 3.1 shows the percentage of water in different structures of the human body. brain 73% eye 95% heart 75% blood 94% kidney 79% lung 83% muscles 75% bones 31% Fig. 3.1 (i) The mean mass of a human eye is 28 g. Using information from Fig. 3.1, calculate the mass of water in a human eye. Give your answer to two significant figures. …… g [2] (ii) Describe the importance of water in the human body. …… [3] (b) Cholera is a disease caused by a pathogen in contaminated water. Fig. 3.2 is a diagram of the cholera pathogen. L M plasmid DNA Fig. 3.2 (i) State the name of structures L and M shown in Fig. 3.2. L …… M …… [2] (ii) Identify two features shown in Fig. 3.2 that are typical of prokaryotes. 1 …… 2 …… [2] (iii) State the type of pathogen that causes cholera. …… [1] (iv) The scientific name for the pathogen that causes cholera is Vibrio cholerae. State the genus name for this pathogen. …… [1] (v) Explain how the cholera pathogen causes dehydration of the human body. …… [3] (vi) Complete the sentences about the use of plasmids in genetic modification. During genetic modification, human DNA and plasmid DNA are cut with a restriction enzyme. This creates …… which are joined together using an enzyme called …… . The modified plasmid containing the human gene is called a …… plasmid. [3] [Total: 17]

Mark scheme

3(a)(i) 27 ;; 2 28 × 95 MP1: 28 × 0.95 = 26.6 or = 26.6 100 MP2: correct rounding to 2 significant figures 3(a)(ii) any three from: 3 1 ref to solvent / described ; 2 for digestion / named example ; 3 for excretion / named example ; 4 for transport / named example ; 5 temperature regulation ; 6 support, cells / tissues ; 7 AVP ; 3(b)(i) L cell membrane ; 2 M ribosome ; 3(b)(ii) any two from: 2 cell wall ; circular DNA ; plasmid(s) ; AVP ;; 3(b)(iii) bacterium ; 1 3(b)(iv) Vibrio ; 1 3(b)(v) any three from: 3 cholera produces a toxin that causes secretion of chloride ions, into, (small) intestine / gut or out of the small intestine cells ; causing osmotic movement of water into the, gut / (small) intestine or out of the (small intestine) cells ; causing diarrhoea / described ; 3(b)(vi) sticky ends ; 3 (DNA) ligase ; recombinant ;

Question 410 marks

Question

(a) Fig. 4.1 shows part of a human placenta and umbilical cord. The arrows show the direction of blood flow. to fetus from fetus Fig. 4.1 (i) Describe the functions of the placenta and the umbilical cord shown in Fig. 4.1. …… [4] (ii) A fetus develops inside an amniotic sac. Describe the functions of the amniotic sac and amniotic fluid. …… [3] (b) Syphilis is a sexually transmitted infection (STI) that can be passed from a mother to her fetus. (i) State the name of one other STI that can be passed from mother to fetus. …… [1] (ii) State two ways to control the spread of STIs. 1 …… 2 …… [2] [Total: 10]

Mark scheme

4(a)(i) 1 maternal and fetal blood are kept separate / AW ; 4 plus any three from: 2 umbilical cord / placenta, transfers named substance, from mother / to fetus ; 3 umbilical cord / placenta, transfers named substance, from fetus / to mother ; 4 umbilical cord / placenta, transfers, antibodies / passive immunity, from mother / to fetus ; 5 placenta forms barrier to, toxins / pathogens ; 6 placenta secretes, progesterone / oestrogen ; 7 AVP ; 4(a)(ii) any three from: 3 1 protects, (fetus) against (mechanical) damage ; 2 regulation of temperature ; 3 allows fetus to move / allows muscle or bone development ; 4 protects fetus from infection / provides antibodies ; 5 allows lung development ; 6 sac produces amniotic fluid ; 7 AVP ; 4(b)(i) HIV / named STI ; 1 4(b)(ii) any two from: 2 (named) barrier method of contraception / condom / femidom ; abstinence ; (regular) testing / screening ; education ; tracing sexual partners ; use of antibiotics ; vaccination ; AVP ;;

Question 512 marks

Question

(a) Fig. 5.1 shows a cross-section of a leaf. T Fig. 5.1 (i) On Fig. 5.1, draw a circle around one vascular bundle. [1] (ii) On Fig. 5.1, draw a label line and the letter X to identify the palisade mesophyll tissue. [1] (iii) State the name of the cell structure in palisade mesophyll cells where photosynthesis occurs. …… [1] (iv) Describe the functions of the tissues in a vascular bundle in a leaf. …… [4] (b) The leaf shown in Fig. 5.1 is from an aquatic plant adapted to live in water. The leaves float on the surface of the water. (i) State the term used to describe plants that are adapted to live in water. …… [1] (ii) Identify feature T shown in Fig. 5.1 and explain how this feature adapts the leaf to float on the surface of the water. feature T …… explanation …… [2] (iii) Explain one other adaptation of this group of aquatic plants. …… [2] [Total: 12]

Mark scheme

5(a)(i) circle drawn around one vascular bundle ; 1 5(a)(ii) X drawn to identify palisade mesophyll tissue ; 1 5(a)(iii) chloroplasts ; 1 5(a)(iv) ref to xylem and phloem ; 4 phloem responsible for, translocation / transport of sucrose or amino acids ; xylem transports, water / mineral ions ; xylem provides support ; 5(b)(i) hydrophyte ; 1 5(b)(ii) T: 2 air space ; explanation: creates buoyancy / decreases density, (of leaf) ; 5(b)(iii) stomata on, upper epidermis / upper side of leaf ; 2 Explanation must be linked to correct allows gas exchange / AW ; description or thin / no, cuticle ; no need to prevent water loss ; or AVP ;;

Question 614 marks

Question

(a) Microplastics are pieces of plastic with a diameter less than 0.5 cm. Fig. 6.1 shows the mass of microplastics in the oceans between 2000 and 2040. The data between 2000 and 2020 is an estimate. The data after 2020 is a prediction. 2.0 1.5 mass of microplastics 1.0 / million tonnes 0.5 0 2000 2010 2020 2030 2040 year Fig. 6.1 (i) Suggest why the mass of microplastics between 2000 and 2020, shown in Fig. 6.1, is an estimate. …… [2] (ii) Using Fig. 6.1, calculate the predicted percentage increase in the mass of microplastics in the oceans between 2000 and 2040. Space for working. ……% [2] (b) Phytoplankton are producers found in the ocean. Phytoplankton absorb microplastics into their cells. (i) Describe what is meant by the term producer. …… [2] (ii) Fig. 6.2 shows a shearwater bird. Shearwater birds feed on fish in the ocean. Fig. 6.2 Suggest how microplastics can end up in consumers such as shearwater birds. …… [2] (iii) The population of shearwater birds is decreasing. Describe three ways the population of shearwater birds can be conserved. 1 …… 2 …… 3 …… [3] (iv) Explain the risks to a population if its population size decreases. …… [3] [Total: 14]

Mark scheme

6(a)(i) any two from: 2 idea that not all microplastics are able to be, collected / measured / weighed ; because the area is, (too) large / inaccessible / deep / undiscovered ; because some microplastics were eaten ; only samples were taken / described ; 6(a)(ii) 750 (%) ;; 2 MP1: both figures identified from graph e.g. 1.7 and 0.2 (million tonnes) or difference found e.g. 1.5 (million tonnes) MP2: correct calculation e.g. 1.5 ÷ 0.2 x 100 = 750 6(b)(i) (organism) makes its own (named organic) nutrients ; 2 using energy from sunlight / through photosynthesis ; 6(b)(ii) any two from: 2 microplastics, can’t breakdown / are non-biodegradable / can’t be excreted ; (microplastic-containing) producers / phytoplankton, are eaten by fish (which are eaten by birds) ; AVP ; 6(b)(iii) any three from: 3 monitoring species ; idea of protecting, habitat / nest sites ; education / awareness ; captive breeding programmes ; ban, hunting / poaching ; 6(b)(iv) any three from: 3 1 reduction in genetic variation ; 2 inbreeding ; 3 less chance of population adapting to a (named) change in the environment ; 4 increased chance of harmful recessive alleles being expressed / increase in genetic disease ; 5 extinction ; 6 idea that more difficult to find a mate ; 7 AVP ;

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Where can I find the 0610/42 February/March 2025 mark scheme?

On this page, free: the mark scheme for IGCSE Biology 0610/42, February/March 2025 (0610_m25_ms_42), and the question paper (0610_m25_qp_42), to read or download, with each question's marking points written out underneath.

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Biology 0610/42 for February/March 2025 is out of 80 marks, with 1 hour 15 minutes to answer it, across 6 questions.

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Yes. Upload your answers to 0610/42/F/M/25 as a PDF or photos, and CIE Buddy marks every question against this paper's official mark scheme, using Cambridge's marking rules. You get your score, each lost mark explained on your own script, and the topics to revise. It's a guide, not an official Cambridge grade.