Biology 0610/41 October/November 2020: question paper and mark scheme
Cambridge IGCSE Biology (0610), Paper 4 Theory (Extended), October/November 2020. Read both free below, or download them. Done the paper? Get it marked by AI against this mark scheme.
Water is an essential molecule for life.
(a) Complete the statements.
Water moves into and out of cells by …… .
Water is known as a …… because it can dissolve solutes.
[2]
(b) A leaf cell was put into a solution. The water potential of the solution was lower than the water potential of the contents of the cell.
Fig. 1.1 is a sketch of the cell after three hours in the solution.
nucleus
Fig. 1.1
The leaf cell was transferred into pure water.
Sketch the expected appearance of the cell after it had been in the pure water for three hours.
Draw one arrow on your sketch to show the direction of water movement.
[3]
(c) A plant was not watered for one week.
Fig. 1.2 shows a series of photographs of the plant during the week.
day 0 day 3 day 7
Fig. 1.2
Explain how the lack of water has affected the support of the leaves of the plant shown in
Fig. 1.2.
Use the term turgor pressure in your answer.
…… [3]
[Total: 8]
Mark scheme
1(a) osmosis ; 2
solvent ;
1(b) drawing with: 3
arrow showing water movement into cell ;
max. two from:
no space between cell membrane and cell wall ;
cell wall, slightly bent outwards / straight ;
vacuole larger in proportion than in Fig 1.1 ;
1(c) wilting ; 3
lack of turgor pressure (at the end of the week) ; ora
no longer a push against cell wall / AW ; ora
(mesophyll) cells not providing support / cell collapses / AW ;
(lack of water means cells become) flaccid / plasmolyse ;
Pathogens cause disease.
(a) Fig. 2.1 shows some cells that are part of the human immune system. These cells are responding to one type of pathogen.
Q
R
T
S
Fig. 2.1
Explain how the immune system responds to an invasion of pathogens.
Use the letters in Fig. 2.1 in your answer.
…… [6]
(b) A vaccine was introduced in 1942 for a particular disease.
Fig. 2.2 shows the effect of introducing the vaccine on the number of cases of the disease in one country.
250 vaccine introduced
200
150 number of cases of disease per million people
100
50
0
1920 1930 1940 1950 1960 1970 1980 year
Fig. 2.2
In 1946 the government of the country concluded that the vaccine was successful.
Discuss the evidence, shown in Fig. 2.2, for and against this conclusion.
…… [4]
[Total: 10]
Mark scheme
2(a) Q / pathogen, are recognized as foreign ; 6
Q / pathogen, will have specific / unique / AW, antigen ;
S and R are white (blood) cells ;
S / lymphocytes, make antibodies ;
T are antibodies ;
T / antibodies are as specific shape / complementary to,
antigen / pathogen / Q ;
T / antibodies bind to, antigen / pathogen / Q ;
ref. to forming memory cells ;
ref. to, active / long-term, immunity ;
R / phagocytes, engulf, pathogens / antigens ;
R / phagocytes, have enzymes / digest pathogens OR antigens ;
AVP ;
2(b) support of conclusion: 4
general decrease, from 1942 / vaccination ;
cases do not return to pre-vaccine levels / AW ;
no cases from 1974 ;
against conclusion:
number of cases increased, (during the 2 years) after the vaccine was
introduced / until government made its conclusion ;
took 32 years after vaccine introduced before no cases of disease ;
but there are (small) peaks (in cases) / fluctuation (in cases) ;
comparative data quote ;
All living organisms excrete waste products.
(a) Fig. 3.1 is a photomicrograph of Naegleria fowleri, a single-celled protoctist that lives in watery environments.
A
magnification ×4000
Fig. 3.1
(i) State a feature of N. fowleri, visible in Fig. 3.1, that distinguishes it from prokaryotes.
…… [1]
(ii) State the name and function of structure A.
structure ……
function ……
[2]
(iii) Suggest how N. fowleri excretes carbon dioxide.
…… [1]
(b) Urea is a toxin that is excreted by the kidneys in humans.
Describe how and where in the body urea is formed.
…… [3]
(c) Fig. 3.2 shows part of the human excretory system and associated blood vessels.
The arrows indicate the direction of blood flow.
D
E
F
G
H not to scale
Fig. 3.2
(i) Draw a label line and the letter X on Fig. 3.2 to show the location of the cortex in one of the kidneys. [1]
(ii) Table 3.1 contains statements about the labelled structures in Fig. 3.2.
Complete the table by:
• stating the name of the structure
• identifying the letter that labels that structure.
Table 3.1
description name of structure letter from Fig. 3.2
organ that stores urine
tube that carries urine out of the kidney blood vessel with the lowest concentration of urea blood vessel with the lowest concentration of carbon dioxide tube that carries urine out of the body
[5]
(d) Doctors wanted to investigate the effect of exercise on the excretion of salts.
They collected urine from people before and after running a long distance on a hot day.
The results of their investigation are shown in Table 3.2.
Table 3.2
before running after running
average volume of urine / cm3 1156.0 569.0
average concentration of sodium in
85.6 78.2 urine / mmol per dm3
(i) Suggest why there is a difference in the volume of urine produced before running compared with after running.
Use the information in Table 3.2 in your answer.
…… [2]
(ii) Calculate the percentage decrease in the average sodium concentration after running compared with before running.
Give your answer to one significant figure.
Space for working.
…… %
[3]
(iii) Describe how the kidney tubules enable the excretion of salts.
…… [3]
(e) Large plasma proteins are usually prevented from entering the urine.
State the name of one protein found in blood plasma.
…… [1]
[Total: 22]
Mark scheme
3(a)(i) any one from: 1
nucleus ;
membrane-bound (named) organelle / has internal membranes ;
vesicles ;
no cell wall ;
3(a)(ii) (cell) membrane ; 2
controls what, enters / leaves, the cell ;
3(a)(iii) diffusion (through cell membrane / A) ; 1
3(b) any three from: 3
breakdown of (excess) amino acids ;
(by) deamination ;
removal of nitrogen containing part (of amino acid) ;
in the liver ;
3(c)(i) X marked on either kidney in the outer / edge region ; 1
3(c)(ii) 5 one mark per correct row
letter from
function name of structure
Fig. 3.2
organ that stores urine bladder G;
tube that carries urine out of
ureter F;
the kidney
blood vessel with the lowest
renal vein D;
concentration of urea
blood vessel with the lowest
renal artery E;
concentration of carbon dioxide
tube that carries urine out of
urethra H;
the body
3(d)(i) any two from: 2
sweat more / lost more water (while running) ;
do not drink as much / reduced intake of water (while running) ;
ref. to homeostasis / negative feedback ;
AVP ;
3(d)(ii) 9(%) ;;; 3 MP1 correct values selected i.e. 78.2 and 85.6
MP2 correct calculation
MP3 correct rounding to one significant figure
ecf for MP2 and MP3 for incorrect MP1
3(d)(iii) any three from: 3
salts are in the blood / move from the blood into the tubule / AW ;
ref. to glomerulus ;
(ultra)filters / allows through ;
pores / gaps, in capillary wall / narrow capillaries ;
small molecules are filtered / large are not filtered / AW ;
(some salt) reabsorption ;
ref. to active transport / diffusion ;
excess (salt) remains in the, urine / filtrate ;
AVP ;
3(e) any one from: 1
fibrinogen / fibrin ;
(named) hormone ;
antibodies ;
(a) Fig. 4.1 shows a bee with pollen on its legs.
Fig. 4.1
Bees are insects that pollinate some flowering plants. They are attracted to the flowers by their colour, scent and nectar.
(i) Describe other ways in which flowers and pollen grains are adapted for insect pollination.
…… [3]
(ii) State where pollen is produced in a flower.
…… [1]
(iii) State the name of the process that produces haploid pollen nuclei.
…… [1]
(iv) Explain why it is important that the pollen nuclei are haploid.
…… [1]
(b) (i) Describe how the pollen that is carried by an insect to another flower results in the formation of a plant embryo.
…… [5]
(ii) Describe the advantages of cross-pollination.
…… [2]
(c) Some people are concerned that genetically modified plants might cross-pollinate with wild varieties of plants.
(i) Suggest how farmers could prevent cross-pollination between genetically modified plants and wild varieties of plants.
…… [1]
(ii) State two advantages of genetically modified crops.
1 ……
2 ……
[2]
[Total: 16]
Mark scheme
4(a)(i) any three from: 3
large / obvious / AW, petals / sepals ;
anthers / stigmas, inside flower ;
filaments are stronger / thicker / AW ;
pollinators must touch anthers, to reach nectar / AW ;
sticky stigma ;
pollen, large ;
pollen, sticky / spiky ;
AVP ; honey guides / landing platforms / mimic insects
4(a)(ii) anther ; 1 A stamen
4(a)(iii) meiosis / reduction division ; 1
4(a)(iv) any one from: 1
so that diploid number restored (after fertilisation) / AW ;
to enable sexual reproduction ;
(so that the offspring) are genetically different / to allow variation ;
4(b)(i) any five from: 5
pollen transferred to stigma ;
ref to (pollen) tube ;
(pollen) tube, growth / germination ;
(pollen tube grows) down style ; MP4 A pollen nucleus moves down style
(pollen tube) enters ovule ;
(ovule is) in the ovary / carpel ;
pollen / male, nucleus fuses with ovule / female, nucleus ;
ref. to fertilisation ;
to form zygote ;
(zygote divides by) mitosis to form an embryo ;
AVP ; e.g. (fertilised) ovule becomes the seed
4(b)(ii) any two from: 2
allows, variation / genetic diversity ;
plant more likely to survive (named) environmental change ;
resistance to disease ;
(ability to) evolve ;
ref. to fitness ;
AVP ;
4(c)(i) any one from: 1 MP1 A isolate plants
grow, GM / wild varieties, in glasshouses ;
cover flowers ;
remove stamens ;
plant another species around the crop ;
make a large, gap / wall, around the field ;
use sterile GM plants ;
grow female plants (only) ;
AVP ;
4(c)(ii) any two from: 2
confer resistance, to a (named) factor ;
provide additional, nutrients / AW (to humans) ;
improved, shelf life / flavour / yield / AW ;
environmental protection idea A less use of pesticides / pollution ;
AVP ;
Milk is a source of some of the nutrients that are part of a balanced diet.
(a) Calcium and protein are two nutrients found in milk.
Describe the importance of calcium and protein in the diet.
calcium ……
protein ……
[4]
(b) Lactose is found in cows’ milk. Some people do not have the enzyme to digest lactose.
State the names of two organs, associated with the alimentary canal, that produce enzymes.
1 ……
2 ……
[2]
(c) Fig. 5.1 shows a flow diagram for the production of lactose-free milk.
Step 1 collect cows’ milk from farm
diagram of Step 4
Step 2 heat milk to a high temperature for 15 seconds milk
Step 3 allow milk to cool to 20°C
beads containing
Step 4 pour milk into a container of enzyme beads containing enzymes
Step 5 collect lactose-free milk
lactose-free milk
Step 6 store lactose-free milk at 2°C in sterile bottles
Fig. 5.1
(i) Explain how heating the milk in step 2 in Fig. 5.1 ensures the hygienic preparation of lactose-free milk.
…… [1]
(ii) Explain why the milk must be cooled in step 3 before it makes contact with the enzymes.
…… [2]
(iii) State the name of the enzyme used to make lactose-free milk in step 4.
…… [1]
(iv) Suggest why the enzymes are kept in the beads in step 4 rather than mixed as an enzyme solution with the milk.
…… [1]
(d) Milk is produced by mammals.
(i) Explain the advantages to newborn mammals of breast milk.
…… [4]
(ii) Explain why breast-feeding mothers are advised to drink plenty of water and avoid excessive alcohol consumption.
…… [2]
[Total: 17]
Mark scheme
5(a) calcium: 4 max. three from either section
(formation of) bones ;
(formation of) teeth ;
prevents rickets ;
AVP ;
protein:
repair, cells / tissues ;
growth ;
used to make, muscle / enzyme / antibodies / protein, channels / carrier ;
prevents marasmus ;
AVP ;
5(b) any two from: 2
salivary glands ;
stomach ;
pancreas ;
small intestine / named part of small intestine ;
5(c)(i) kills, bacteria / microorganisms / pathogens ; 1
5(c)(ii) any two from: 2
(heat) denatures enzymes ;
so lactose, not broken down / not digested ; MP2 A not optimum temperature, for
digestion / AW
changes shape of active site ;
enzyme will not fit substrate ;
5(c)(iii) lactase ; 1
5(c)(iv) any one from: 1 ora throughout
can reuse the enzyme ;
cheaper ;
no enzymes left in milk ;
so milk does not need to be purified ;
AVP ; e.g. enzymes more stable / less likely to denature
/ affects taste / drinking the enzyme might trigger allergies
5(d)(i) any four from: 4
contains antibodies / ref. to colostrum / provides protection against,
pathogens / diseases / microorganisms ;
provides passive immunity ;
nutrient requirements met / change with age / change with development ;
easy to digest / AW ;
no additives / less risk of allergies ;
sterile / less risk of infection / AW ;
is at, body / correct, temperature ;
no preparation / always available / convenient ;
bonding with mother / AW ;
free / cheap ;
idea of volume is controlled / no over-feeding ;
AVP ;
5(d)(ii) any two from: 2
water needed to, produce breast milk / stay hydrated / AW ;
alcohol can pass to the baby in breast milk / AW ;
alcohol can harm / delay development of, baby / AW ;
AVP ;
Sensitivity is one of the characteristics of all living organisms.
(a) Define the term sensitivity.
…… [2]
(b) The eye is an example of a sense organ.
(i) Define the term sense organ.
…… [2]
(ii) Adrenaline is a hormone that is released in ‘fight or flight’ situations. It causes a change in the eye.
Complete Table 6.1 by stating the parts of the eye that change when adrenaline is released into the blood.
Table 6.1
action part of the eye
muscle that relaxes
muscle that contracts
widens
[3]
[Total: 7]
Mark scheme
6(a) (the ability to) detect stimuli (in the internal / external environment) ; 2
to make (appropriate) responses ;
6(b)(i) groups of receptor cells ; 2
responding to specific stimuli ;
6(b)(ii) 3
action structure
relaxes circular muscles (of the iris) ;
contracts radial muscles (of the iris) ;
widens pupil ;
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Biology 0610/41 for October/November 2020 is out of 80 marks, with 1 hour 15 minutes to answer it, across 6 questions.
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