Biology 0610/43 May/June 2020: question paper and mark scheme
Cambridge IGCSE Biology (0610), Paper 4 Theory (Extended), May/June 2020. Read both free below, or download them. Done the paper? Get it marked by AI against this mark scheme.
(a) State three uses of energy in the human body.
1 ……
2 ……
3 ……
[3]
(b) Fig. 1.1 shows part of the digestive system of a human.
A
diaphragm
B
L
K
C
H
G
D
F
E
Fig. 1.1
Complete Table 1.1. One row has been done for you.
Table 1.1
function name of structure letter from Fig. 1.1
pushes food to the stomach oesophagus A
assimilation of amino acids to produce plasma proteins
storage of bile
secretion of insulin
absorption of fatty acids and glycerol
secretion of pepsin
digestion of starch
[6]
(c) Describe the role of the liver in the recovery from oxygen debt after strenuous exercise.
…… [2]
(d) Alcohol is a drug.
Define the term drug.
…… [2]
(e) (i) State two immediate effects of excessive alcohol on the body.
1 ……
2 ……
[2]
(ii) State two long-term effects of excessive alcohol on the body.
1 ……
2 ……
[2]
(f) Pregnant women are advised not to drink alcohol as it may have harmful effects on the fetus.
(i) Outline these harmful effects.
…… [2]
(ii) State two harmful substances other than alcohol that can cross the placenta.
1 ……
2 ……
[2]
[Total: 21]
Mark scheme
1(a) any three from: 3
protein synthesis ;
transport in the phloem ;
cell division / mitosis / meiosis ;
active transport / absorption of ions (from the soil) ;
growth ;
movement / muscular contraction ;
sensitivity ;
nerve impulses ;
AVP ;;;
1(b) one mark per correct row 6
function name of structure letter from Fig. 2.1
pushes food through
oesophagus A
the stomach
assimilation of amino
acids to produce liver K
plasma proteins
storage of bile gall bladder L
secretion of insulin pancreas C
absorption of fatty acids
small intestine H/D
and glycerol
secretion of pepsin stomach B
digestion of starch small intestine H/D
;;;;;;
1(c) any two from: 2
lactic acid is produced, in muscles / during exercise ;
by anaerobic respiration ;
liver absorbs lactic acid from the blood ;
(aerobic) respiration / oxidation / breakdown, of lactic acid ;
to carbon dioxide and water ;
1(d) any substance taken into the body ; 2
that modifies or affects chemical reactions in the body ;
1(e)(i) any two from: 2
depressant ;
lengthens reaction time(s) ;
reduces self-control ;
any appropriate effect on the nervous system described ;
AVP ;
1(e)(ii) any two from: 2
addiction ;
liver damage ;
AVP ;;
1(f)(i) any two from: 2
miscarriage ;
premature birth ;
low birth weight ;
addiction / dependence ;
fetal alcohol syndrome (FAS) ;
AVP ;
1(f)(ii) any two from: 2
nicotine ;
pathogens / virus ;
any example ; e.g. HIV / rubella
(named) heavy metal(s) ; e.g. lead / mercury
carcinogen(s) ;
(named) toxin(s) ; e.g. pesticides
(named) medicinal drugs ;
(named) misused (illegal) drugs ; e.g. heroin
(a) Fig. 2.1 shows the human population of a country between 1910 and 2020.
140
120
100 number of people 80
/ million
60
40
20
0
1900 1920 1940 1960 1980 2000 2020 year
Fig. 2.1
(i) Calculate the percentage increase in the population of the country between 1940 and
2020.
Space for working.
……%
[3]
(ii) Describe the factors that could cause the change in the population size between 1940 and 2020, shown in Fig. 2.1.
…… [3]
(b) Some countries have invested in biofuels such as ethanol, biomass and biodiesel.
(i) Describe how ethanol can be made by microorganisms.
…… [2]
(ii) Some countries use large areas of land to grow maize plants. This crop plant can be used to produce biofuels.
Discuss the negative impact on the environment of growing large-scale monocultures of crop plants such as maize.
…… [4]
[Total: 12]
Mark scheme
2(a)(i) population in 1940 = 20 million, population in 2018 = 136 million ; 3
580% ;;
2(a)(ii) any three from: 3
increase in birth rate / decrease death rate ;
immigration ;
increased food supply ;
reduced poverty ; ora
better housing / sanitation / health care / vaccination / AW ;
AVP ;
2(b)(i) by yeast ; 2
(using) anaerobic respiration ;
2(b)(ii) any four from: 4
deforestation ;
loss in (variety) of, habitat / places where organisms live / described ;
disruption to food chains / described ;
loss of (bio)diversity / (local) extinction of species / species become endangered / AW ;
soil erosion / increased risk of landslides / flooding ;
disrupted nutrient cycling ;
decrease in (soil) water / desertification ;
outbreaks / spreading, of crop diseases ;
outbreaks / spreading, of (named) pests ;
overuse of herbicides ;
overuse of, pesticides / insecticides / AW ;
killing of non-target species ;
pollution of waterways by, plant nutrients / fertilisers ;
pollution of the atmosphere by NOx from fertilisers ;
pollution by use of fossil fuels in machinery ;
AVP ;
The American writer Ernest Hemingway lived on the island of Key West in Florida, USA in the
1930s. During this time he was given a male cat by a sea captain.
The cat had more toes than usual. This inherited condition is called polydactyly. The allele for polydactyly is dominant.
(a) Define the term inheritance.
…… [1]
(b) Fig. 3.1 is part of a pedigree diagram for Hemingway’s cats.
1 2
3 4 5 6 7 8 9 10
11 12 13 14 15 16
Key:
17 female cat with normal female cat with number of toes polydactyly
male cat with normal male cat with number of toes polydactyly
Fig. 3.1
(i) State the genotypes of cats 5, 6 and 14 in the pedigree diagram in Fig. 3.1.
Use the letters T and t.
cat 5 ……
cat 6 ……
cat 14 ……
[3]
(ii) Explain why none of the offspring of cats 3 and 4 have inherited polydactyly.
Use the information in Fig. 3.1 in your answer.
…… [1]
(c) Scientists published the results of an investigation into the DNA of cats with and without polydactyly. They compared the base sequence from a particular region of DNA that controls the development of the limbs.
Table 3.1 shows the base sequences.
Table 3.1
cats without polydactyly AGA CAC AGA AAT GAG
Hemingway’s cats with polydactyly AGA CAC GGA AAT GAG cats with polydactyly from Oregon and Missouri in the USA AGA CAC GGA AAT GAG cats with polydactyly from the UK AGA CAC AGT AAT GAG
(i) Describe how the base sequences of the cats with polydactyly differ from the base sequence of cats without polydactyly.
…… [2]
(ii) State the name of the process by which base sequences in DNA are changed.
…… [1]
(iii) The base sequences in Table 3.1 provide evidence that indicates which country the male cat given to Hemingway in the 1930s came from.
Suggest which country this cat came from and give a reason for your choice.
…… [2]
(d) Fig. 3.2 shows part of a DNA molecule from a chromosome of a cat.
Complete Fig. 3.2 by writing the letters for the base sequence of the other strand of the DNA molecule.
T ……
A ……
A ……
T ……
G ……
C ……
G ……
T ……
G ……
Fig. 3.2
[1]
(e) Explain why polydactyly is an example of discontinuous variation.
…… [2]
[Total: 13]
Mark scheme
3(a) transmission of genetic information from generation to generation ; 1
3(b)(i) Tt ; 3
tt ;
TT / Tt ;
3(b)(ii) cats 3 and 4 are homozygous recessive / do not have the allele for polydactyly ; 1
3(c)(i) any two from: 2
cats with normal number of toes have AGA for bases 7, 8 and 9 ;
cats with polydactyly have GGA or AGT ;
bases 7 and 9 are different / base 7 is G not A in the USA cats / base 9 is T not A in the UK cats ;
3(c)(ii) mutation ; 1
3(c)(iii) origin of the cat was USA ; 2
base sequence is the same as the other cats from the USA / they have the same, mutation/base sequence, as the
Oregon and Missouri cats ;
3(d) 1
T A
A T
A T
T A
G C
C G
G C
T A
G C
;
3(e) distinct, phenotypes / categories ; 2
no intermediates / phenotypes not on a continuous scale ;
Xerophytes grow in habitats with low rainfall and soils that often have high concentrations of salts.
Fig. 4.1 shows the xerophyte Yucca treculeana growing on salt flats.
Y. treculeana
Fig. 4.1
(a) (i) Explain how xerophytes, such as Y. treculeana, are adapted to absorb sufficient water in the conditions in which they live.
…… [4]
(ii) Explain how xerophytes are adapted to reduce water loss to the atmosphere.
…… [3]
(iii) Xerophytes often have many defence mechanisms that reduce or prevent herbivores eating them.
Suggest how xerophytes protect themselves against herbivores.
…… [2]
(b) Forest ecosystems can be affected by acid rain.
Describe how the production of acid rain and its effects on forest ecosystems can be reduced.
…… [4]
[Total: 13]
Mark scheme
4(a)(i) any four from: 4
deep roots / AW ;
to absorb water from the water table / AW ;
long and spread out below the surface ;
to absorb water when it rains ;
root cells have low water potential ;
to absorb water by osmosis ;
from (very) salty soils / AW ;
roots branch many times ;
have many roots hairs ;
to give a large surface area (for absorption of water) ;
4(a)(ii) any three from: 3
few stomata / low stomatal density ;
sunken stomata ;
stomata close during the day and open at night ;
rolled leaves ;
thick epidermis / thick cuticle ;
few / no / small, leaves ;
hairs on leaves ;
low rates of transpiration ;
AVP ;;
4(a)(iii) any two from: 2
make / store, toxins ;
make / store, foul-tasting substances / AW ;
spines / prickles / needles ;
resins (that trap insects) ;
thick (inedible) leaves ;
AVP ;;
4(b) any three from: 4
reduce air pollution ;
reduce emissions of, sulfur dioxide ;
use filters / ‘scrubbers’ on chimneys ;
catalytic converters ;
reduce use of (named) fossil fuel(s) ;
example of way to reduce demand for energy ;
use low-sulfur (fossil) fuels ;
use alternative sources of power ;
add lime to soils ;
to reduce mobilisation of aluminium in soils / AW ;
to raise pH of soils ;
AVP ;
Bacteria are classified in the Prokaryote kingdom.
(a) State two features of animal and plant cells that are not found in prokaryotes.
1 ……
2 ……
[2]
(b) Methicillin-resistant Staphylococcus aureus (MRSA) is a type of bacterium that is resistant to some antibiotics.
Fig. 5.1 shows how a population of bacteria may develop antibiotic resistance and how the antibiotic resistance can be passed from one strain of bacterium to another.
population of pathogenic bacteria A in patient 1
treatment with antibiotic Z started
population of pathogenic bacteria A in patient 1 in the middle of treatment with antibiotic Z
population of pathogenic bacteria A in patient 1 when treatment with antibiotic Z was stopped
transmission of bacteria A to patient 2
bacteria A and B in patient 2
not to scale
Key: bacterium of strain A bacterium of strain B resistant to antibiotic Z resistant to antibiotic Z bacterium of strain A bacterium of strain B not resistant to antibiotic Z not resistant to antibiotic Z dying bacterium of strain A plasmid
Fig. 5.1
Explain how resistance to an antibiotic develops in a population of bacteria and spreads in the human population.
…… [6]
(c) Explain how the development of resistant bacteria, such as MRSA, can be minimised.
…… [3]
[Total: 11]
Mark scheme
5(a) any two from: 2
nucleus / nuclear membrane / nuclear envelope ;
(linear) chromosomes ;
mitochondrion ;
endoplasmic reticulum ;
vacuoles / vesicles ;
AVP ;
5(b) any six from: 6
resistance arises by mutation ;
in small number of bacteria ;
ref. to a random event (not related to presence of antibiotic) ;
antibiotic kills bacteria that do not have the mutation / AW ;
resistant bacteria have no competition ;
resistant bacteria reproduce ;
pass on, gene / allele, for resistance ;
natural selection ;
method of transmission from one person to another described ;
gene transferred to other bacteria (of different type) in a plasmid ;
AVP ;
5(c) any three from: 3
prescribe / use, antibiotics less often ;
do not use for, viral / fungal, infections ;
make sure people complete the course of antibiotics / AW ;
develop new antibiotics ;
do not use the same antibiotics for too long / rotate antibiotics / AW ;
use combinations of antibiotics ;
AVP ;; e.g. isolation of patients with antibiotic-resistant infections / good hygiene to prevent spread of infection / reduce
use of antibiotics in farming
In many parts of the world dairy cattle are kept in large barns and reared intensively, as shown in
Fig. 6.1.
Fig. 6.1
(a) Food for cattle that are reared intensively includes cereals, such as maize and barley.
Ecologists have calculated that it is more energy efficient to grow crops for human consumption than for food for livestock.
Explain why intensive rearing of livestock is not an efficient use of crops.
…… [3]
(b) The urine and faeces from cattle kept in barns is removed and treated in the same way as human sewage to avoid polluting the aquatic environment.
Outline the effects of untreated waste from cattle on the aquatic environment.
…… [4]
(c) Intensive livestock production could be one way of preventing famine.
Describe the causes of famine.
…… [3]
[Total: 10]
Mark scheme
6(a) any three from: 3
if crops are used as food for humans fewer trophic levels in the food chain ;
energy lost at each trophic level in the food chain ;
90% energy lost / only 10% energy passed on ;
energy is lost from the cattle ;
any two examples of energy loss from cattle ;;
therefore less energy available to humans ;
AVP ;
6(b) any four from: 4
smell / visual pollution ;
increase risk of water-borne disease ;
increase organic content of, rivers / lakes ;
increase growth of, bacteria / decomposers ;
bacteria / decomposers, use up dissolved oxygen ;
death of (named) organisms that rely on dissolved oxygen ;
eutrophication ;
adds, urea / ammonia ;
increases plant growth ;
AVP ;;
6(c) any three from: 3
lack of food supply / unequal distribution of food ;
wars / sudden immigration, with inadequate resources for the population ;
drought / floods, destroy crops / kill livestock ;
disease in, food plants / animals ;
poverty ;
AVP ;;
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Biology 0610/43 for May/June 2020 is out of 80 marks, with 1 hour 15 minutes to answer it, across 6 questions.
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