Question
Carbohydrates are an important component of a balanced diet.
The flow chart in Fig. 3.1 shows some of the processes that happen to carbohydrates in food that is eaten.
ingestion of large biological molecules
chemical digestion
absorption into the blood via the alimentary canal
increase in blood glucose concentration
assimilation in the liver
Fig. 3.1
(a) Describe what happens to carbohydrates in the human body between ingestion and assimilation in the liver.
Use the information in Fig. 3.1 as a guide.
…… [8]
(b) Mineral salts are another important component of a balanced diet.
State the importance of calcium ions and iron ions in a balanced diet.
calcium ions ……
iron ions ……
[4]
(c) Consuming too much of some mineral salts, such as sodium chloride, increases the risk of developing coronary heart disease (CHD).
Doctors studied the effect of diet on the risk of developing CHD.
The doctors first selected volunteers who had a high salt diet.
The doctors assessed the volunteers’ overall risk of developing CHD and monitored their blood pressure.
(i) List two factors, other than diet and blood pressure, that the doctors considered when assessing the overall risk of the volunteers developing CHD.
1 ……
2 ……
[2]
(ii) The doctors used urine tests to identify volunteers who had a high salt diet.
Explain why urine tests are a good indicator of how much salt has been consumed.
…… [2]
(d) The volunteers were divided into two groups.
The mass of salt consumed by both groups was changed every 4 weeks:
• low salt intake for 4 weeks
• medium salt intake for 4 weeks
• high salt intake for 4 weeks.
In addition, group 2 was given other changes to their diet but group 1 was not.
(i) Suggest one component of the diet of group 2, other than salt, that the doctors changed to further reduce the risk of developing CHD.
…… [1]
The systolic blood pressure of the volunteers was measured every 4 weeks.
These results are shown in Fig. 3.2.
18.0
Key:
17.5 group 1 group 2 average systolic 17.0 blood pressure
/ kPa 16.5
16.0
15.5
15.0 low medium high salt intake
Fig. 3.2
(ii) Calculate the percentage increase in the average systolic blood pressure of the group 1 volunteers when they increased their salt intake from low to high.
low salt intake …… kPa
high salt intake …… kPa
Give your answer to the nearest whole number.
Space for working.
…… %
[3]
(iii) The doctors concluded that some diets reduce the risk of CHD.
Give evidence from Fig. 3.2 to support this conclusion.
…… [3]
[Total: 23]
Mark scheme
3(a) 1 ingestion / digestion / described, occurs in mouth ; 8
2 chemical digestion / absorption / described, occurs in
small intestine / duodenum / ileum ;
ingestion of large biological molecules
3 mechanical / physical, digestion / breaking,
carbohydrate / food, into small pieces ;
4 ref to chew / grind / bite / by teeth / tongue / swallow /
moves through oesophagus / churned in stomach ;
chemical digestion
5 breakdown insoluble molecules into (smaller) soluble
molecules ;
6 salivary (glands) / pancreas, secrete amylase ;
7 amylase breaks down, starch, to, maltose / glucose /
sugar ;
8 maltase is on epithelium of the, small intestine /
duodenum / ileum ;
9 maltase breaks down maltose to glucose ;
10 bile neutralizes (stomach) acid ;
11 ref to neutral / 7 / 8 pH for, amylase / maltase ;
absorption into the blood via the alimentary canal
12 by diffusion / active transport, into villi / microvilli /
capillaries ;
13 microvilli / villi / folds, increase the surface area (for
absorption) ;
increased blood glucose concentration
14 insulin, secreted / produced / AW, from pancreas ;
15 insulin reduces blood glucose concentration ;
16 ref to negative feedback / homeostasis / described ;
3(a) assimilation in the liver
17 glucose, stored as / converted to, glycogen (in liver) ;
18 (assimilated) into, cell / tissues to become part of cell /
ref. to respiration / for release of energy ;
3(b) calcium ion: 4
for (the formation / maintenance, of healthy / strong)
bones ;
for (the formation / maintenance, of healthy / strong) teeth ;
AVP ;;
iron ions:
found in / AW, haemoglobin (molecule) / red blood cell ;
transport oxygen ;
prevent anaemia ;
3(c)(i) stress ; 2
smoking ;
genetic predisposition / family history ;
age ;
sex ;
activity level / AW ;
any pre-existing medical conditions / AW ; alcohol / drug /
medication ;
obesity / weight / mass / BMI / AW ;
3(c)(ii) (excess) salt is, excreted / removed from body (in urine) ; 2
some salt is (re)absorbed in the, kidney / tubules / into the
blood ;
people are not reliable in recording / remembering
/ measuring how much salt they eat ;
3(d)(i) (reduce) fat / cholesterol ; 1
(increase) fibre / roughage ;
(increase) water ;
3(d)(ii) low = 16.8 (kPa) and high = 17.7 (kPa) ; 3
5(%) ;;
3(d)(iii) low salt diets reduce (systolic) blood pressure / risk of 3
CHD ; ora
modified diets / group 2, reduce (systolic) blood pressure
/ risk of CHD ; ora
any description of an interaction between the salt diet and
modified diets together affecting the, blood pressure / risk of
CHD ;
comparative data quote with units ;