Biology 0610/22 February/March 2025: question paper and mark scheme
Cambridge IGCSE Biology (0610), Paper 2 Multiple Choice (Extended), February/March 2025. Read both free below, or download them. Done the paper? Get it marked by AI against this mark scheme.
The relationships of four species of bacteria, P, Q, R and S, were compared.
● Species P and Q have a more recent common ancestor than either species has with species R.
● Species S developed recently from species P.
Which species has the least similar base sequences in their DNA compared to the other three species of bacteria?
A P B Q C R D S
Which structures are found in both plant cells and bacterial cells?
cell membrane cell wall plasmid ribosomes
A yes yes yes no
B no yes yes yes
C yes no yes yes
D yes yes no yes
The diagram shows four mesophyll cells, W, X, Y and Z. Water moves through these cells.
W X Y Z
Which arrow shows the direction of movement of water through these cells?
direction of water water potential / kPa movement
W X Y Z
A → –600 –450 –350 –250
B → –350 –400 –450 –600
C ← –400 –450 –500 –550
D ← –200 –300 –350 –450
Three processes are listed.
1 Molecules or ions are moved across membranes.
2 Molecules or ions are moved by protein carriers.
3 Ions are taken up by root hairs.
Which processes can involve active transport?
A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
Which statement describes enzymes?
A Enzymes are carbohydrates.
B Enzymes are involved in metabolic reactions.
C Enzymes decrease the rate of reaction.
D Enzymes have the same shape of active site as their substrate.
The graphs show how the rate of photosynthesis and the rate of respiration in a plant changed over a 24-hour period.
Which graph shows the correct rate of photosynthesis and rate of respiration?
key photosynthesis respiration
A B
rate rate
/ arbitrary / arbitrary units units
0 0
0 4 8 12 16 20 24 0 4 8 12 16 20 24 time of day / hour time of day / hour
C D
rate rate
/ arbitrary / arbitrary units units
0 0
0 4 8 12 16 20 24 0 4 8 12 16 20 24 time of day / hour time of day / hour
The photomicrograph shows part of the lower surface of a leaf.
X
What is the structure labelled X?
A guard cell
B palisade mesophyll cell
C spongy mesophyll cell
D xylem vessel
A student is told that their diet is not balanced and they may be at risk of developing scurvy.
What should the student do to reduce their risk of scurvy?
A The student should drink more milk which will provide more calcium.
B The student should drink more milk which will provide more vitamin C.
C The student should eat more citrus fruits which will provide more calcium.
D The student should eat more citrus fruits which will provide more vitamin C.
The diagram shows the four types of human tooth.
1 2 3 4 incisor canine premolar molar
Which teeth are used for grinding food?
A 1 and 2 B 1 and 4 C 2 and 3 D 3 and 4
Which conditions cause the highest rate of transpiration?
A high temperature, high wind speed and high humidity
B high temperature, high wind speed and low humidity
C low temperature, low wind speed and low humidity
D low temperature, low wind speed and high humidity
The diagram shows a heart defect that some babies are born with.
The arrows indicate direction of blood flow.
heart defect
Which statement explains why this heart defect might cause the baby to have poor growth?
A Blood flows to the lungs at high pressure increasing rate of gas exchange.
B Blood flows to the lungs at low pressure decreasing rate of gas exchange.
C Mixing of blood results in less oxygen available for respiration.
D Mixing of blood results in more glucose available for respiration.
The diagram shows the effect of vaccination on the human body. Three components in the diagram are represented by numbers.
1
immune response
2 3
can provide passive provide long-term immunity to others immunity
Which components are memory cells?
A 1 only B 2 and 3 C 2 only D 3 only
Yeast can respire aerobically and anaerobically.
For each molecule of glucose used in yeast, how many more molecules of carbon dioxide gas are produced by aerobic respiration compared with anaerobic respiration?
A 1 more
B 2 more
C 4 more
D 6 more
A specific eye condition can cause permanent contraction of the ciliary muscles.
Which row is correct for an eye with this condition compared to an eye without this condition?
suspensory refraction of light ligaments rays onto the retina
A slack less
B slack more
C taut less
D taut more
The liver and the pancreas work together to control the concentration of glucose in the blood.
Which statement is correct?
A The liver converts the small molecule glucose into the large molecule glucagon.
B The liver releases the hormone insulin when blood glucose concentration is too high.
C The pancreas does not respond to an increase in blood glucose concentration.
D The pancreas responds to a fall in the blood glucose concentration by increasing the release of the hormone glucagon.
In the dark, plant shoots grow upwards and roots grow downwards.
What causes these responses?
gravitropism phototropism
A no no
B no yes
C yes no
D yes yes
What is the reason why antibiotics should be used only when essential?
A It increases the artificial selection of antibiotic resistant bacteria.
B It increases the natural selection of antibiotic resistant bacteria.
C It reduces the artificial selection of antibiotic resistant bacteria.
D It reduces the natural selection of antibiotic resistant bacteria.
Which row describes self-pollination?
pollen transferred from pollen transferred from an pollen transferred an anther to the stigma anther to the stigma of a from an anther to of a different flower on flower on a different plant the stigma of the the same plant of the same species same flower
A key
B = yes
C = no
D
The list shows terms used when describing sexual reproduction.
1 male gamete
2 female gamete
3 ovule
4 ovary
5 filament
6 fertilisation
7 haploid
Which terms are used only when describing sexual reproduction in plants?
A 1 and 7 B 2 and 4 C 2 and 6 D 3 and 5
Which statement correctly describes the effect of a hormone in a human menstrual cycle that lasts for 28 days?
A FSH causes maturation of an egg up to day 21.
B LH stimulates the release of an egg on day 14.
C Oestrogen maintains the uterus lining between days 14 and 28.
D Progesterone causes the repair and thickening of the uterus lining between days 4 to 14.
Which statement about the sex chromosomes is correct?
A Men and women can inherit characteristics controlled by genes on the X chromosome.
B Men and women can inherit characteristics controlled by genes on the Y chromosome.
C Only men can inherit characteristics controlled by genes on the X chromosome.
D Only women can inherit characteristics controlled by genes on the Y chromosome.
The graph shows how the mass of DNA changes during a mitotic cell division.
Where on the graph are two cells formed?
A B C D
mass of
DNA per cell
/ arbitrary units
time / hours
A man with blood group A and genotype IAIo has a child with a woman who has blood group B and genotype IBIo.
What is the probability of the child having blood group O?
A 0.00 B 0.25 C 0.50 D 1.00
What are sources of genetic variation in populations?
A meiosis, mutation, random mating
B meiosis, random mating, asexual reproduction
C mitosis, mutation, random fertilisation
D mitosis, random fertilisation, asexual reproduction
The food chain shows how energy is transferred to a human.
lettuce → snails → duck → human
Where did the energy in the lettuce come from?
A snails
B soil
C the Sun
D water
The processes listed affect the concentration of carbon dioxide in the atmosphere.
1 increased deforestation
2 increased tree planting
3 decreased fossil fuel combustion
4 increased fossil fuel combustion
Which processes increase the concentration of carbon dioxide in the atmosphere?
A 1 and 3 B 1 and 4 C 2 and 3 D 2 and 4
A coral reef contains species such as stony corals, sponges, seahorses and whale sharks.
These species interact with each other and are affected by the temperature, salt concentration and oxygen concentration of the water.
Using all the information given, what is being described?
A community
B ecosystem
C food web
D population
What can cause an increase in the size of a rabbit population?
A an increase in a disease that affects rabbits
B an increase in available food for the rabbits
C an increase in pollution in the habitat of the rabbits
D an increase in predation of rabbits
How does eutrophication lead to the death of fish?
A A sudden increase in the number of bacteria increases the spread of disease.
B Algae respire instead of photosynthesise.
C Decomposer bacteria lower the oxygen concentration in the water.
D Fertilisers reduce the availability of nitrates in the water.
It's multiple choice: one mark for each correct answer, and nothing taken off for a wrong one. The mark scheme is the answer key.
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Where can I find the 0610/22 February/March 2025 mark scheme?+
On this page, free: the mark scheme for IGCSE Biology 0610/22, February/March 2025 (0610_m25_ms_22), and the question paper (0610_m25_qp_22), to read or download, with each question's marking points written out underneath.
How many marks is 0610/22 out of?+
Biology 0610/22 for February/March 2025 is out of 40 marks, with 45 minutes to answer it.
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Yes. Upload your answers to 0610/22/F/M/25 as a PDF or photos, and CIE Buddy marks every question against this paper's official mark scheme, using Cambridge's marking rules. You get your score, each lost mark explained on your own script, and the topics to revise. It's a guide, not an official Cambridge grade.